Effect of Epigallocatechin-3-Gallate on Graft-Versus-Host Disease
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is often complicated by alloreactive donor T-cell-mediated graft-versus-host disease (GvHD).The major polyphenol of green tea, epigallocatechin-3-gallate (EGCG), is an Cameras inhibitor of both DNA methyltransferase 1 (DNMT1) and signal transducer and activator of transcription 1 (STAT1